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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Adam Eaton | 2000-2012 | .158 | 0 | 11 | 69 | 44 | 11 | 4.39 | 724 |
| Anibal Echevarria | 2012-2029 | .093 | 0 | 16 | 70 | 106 | 61 | 4.93 | 634 |
| José Echevarría | 2023-2033 | .330 | 389 | 1285 | 0 | 0 | 0 | 0.00 | 0 |
| Jim Edmonds | 1993-2008 | .299 | 317 | 1118 | 0 | 0 | 0 | 0.00 | 0 |
| Charles Edmonson | 2010-2024 | .135 | 1 | 36 | 131 | 122 | 19 | 3.85 | 1548 |
| Alex Edwards | 2029-2030 | .167 | 0 | 2 | 0 | 0 | 0 | 0.00 | 0 |
| Brandon Edwards | 2009-2020 | .049 | 0 | 4 | 54 | 49 | 273 | 2.75 | 838 |
| Joel Edwards | 2013-2018 | .106 | 1 | 8 | 41 | 37 | 17 | 3.70 | 449 |
| Joey Eischen | 1994-2007 | .086 | 0 | 3 | 39 | 22 | 11 | 3.79 | 416 |
| Scott Elarton | 1998-2000 | .156 | 0 | 1 | 28 | 13 | 3 | 4.14 | 308 |
| Clarence Eldridge | 2017-2025 | .266 | 72 | 274 | 0 | 0 | 0 | 0.00 | 0 |
| Alonso Elías | 2031-2033 | .279 | 45 | 148 | 0 | 0 | 0 | 0.00 | 0 |
| Bob Ellis | 2019-2031 | .195 | 6 | 31 | 63 | 65 | 2 | 5.19 | 927 |
| John Elmore | 2029-2033 | .364 | 0 | 3 | 14 | 14 | 33 | 4.16 | 253 |
| Ryan Elmore | 2022-2033 | .286 | 286 | 1052 | 0 | 0 | 0 | 0.00 | 0 |
| Devin Elphinston | 2015-2015 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Juan Encarnacion | 1997-2006 | .262 | 95 | 396 | 0 | 0 | 0 | 0.00 | 0 |
| Benton Engels | 2006-2015 | .270 | 217 | 770 | 0 | 0 | 0 | 0.00 | 0 |
| Morgan Ensberg | 2005-2008 | .207 | 15 | 34 | 0 | 0 | 0 | 0.00 | 0 |
| Alberto Escalera | 2011-2014 | .224 | 9 | 36 | 0 | 0 | 0 | 0.00 | 0 |
| Nicolás Esparza | 2026-2032 | .156 | 0 | 2 | 15 | 14 | 4 | 5.85 | 311 |
| Felipe Espinoza | 2022-2033 | .182 | 2 | 29 | 60 | 49 | 10 | 5.09 | 533 |
| Rafael Espinoza | 2030-2033 | .114 | 0 | 1 | 6 | 9 | 2 | 5.00 | 221 |
| Nate Espy | 2004-2010 | .241 | 79 | 269 | 0 | 0 | 0 | 0.00 | 0 |
| Bobby Estalella | 2006-2006 | .250 | 0 | 3 | 0 | 0 | 0 | 0.00 | 0 |
| Shawn Estes | 1995-2006 | .153 | 3 | 26 | 77 | 78 | 1 | 4.50 | 1062 |
| Eduardo Estrada | 2020-2020 | .000 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 |
| Johnny Estrada | 2001-2009 | .242 | 26 | 111 | 0 | 0 | 0 | 0.00 | 0 |
| José Estrada | 2032-2033 | .217 | 0 | 2 | 0 | 0 | 0 | 0.00 | 0 |
| José Estrada | 2019-2020 | .000 | 0 | 0 | 0 | 0 | 0 | 5.06 | 6 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| Orlando Estrada | 2029-2033 | .233 | 16 | 56 | 0 | 0 | 0 | 0.00 | 0 |
| Damon Evans | 2031-2033 | .096 | 0 | 7 | 11 | 11 | 7 | 3.94 | 210 |
| Elvis Evans | 2030-2033 | .429 | 0 | 0 | 11 | 5 | 5 | 3.46 | 179 |
| Adam Everett | 2001-2011 | .253 | 0 | 22 | 0 | 0 | 0 | 0.00 | 0 |
| Clint Everts | 2009-2017 | .136 | 0 | 1 | 16 | 20 | 3 | 5.55 | 324 |
| Brian Ewing | 2033-2033 | .059 | 0 | 1 | 11 | 10 | 0 | 4.51 | 181 |
| Scott Eyre | 1997-2009 | .101 | 1 | 6 | 64 | 61 | 17 | 4.17 | 779 |
